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Support For Healthy Immune Function

September 5, 2024

Healthy habits and nutritional protocols to help support a healthy, well-functioning immune system.

Immune System Health Support


Our immune system plays a pivotal role in our overall health by protecting the body from exogenous immune challenges. Our body works continuously to keep our immune system in homeostasis so that it is neither underactive nor overactive. Key components of the immune system include the skin, spleen, thymus, tonsils, adenoids, mucous membranes, bone marrow, gut, microbiome, lymphatic vessels, lymph nodes, and lymph fluid.

Because 70% of immune system cells are in the gut, supporting proper digestive health and gut function is imperative for balanced immune activity. A diverse, healthy microbiome is an essential element of the immune system. While everyone can benefit from immune support, populations that may warrant additional immune consideration include the elderly, those with current diseases and comorbidities, pregnant women, and young children.

Implementing specific lifestyle habits and nutritional interventions can support a healthy, well-functioning immune system.


Supportive Lifestyle Practices


Sleep has been found to bolster the immune system, while lack of adequate sleep can increase the risk of infection. Research has shown that adults should get at least 7 hours of sleep per night to support optimal health.


Daily movement is beneficial to the lymphatic system. Movement and exercise stimulate lymph fluid to flow throughout our body and promote the excretion of unwanted bacteria, viruses, and toxins via our lymphatic system.


As chronic stress can impair the function of the immune system, stress-relieving activities should be considered as adjunctive support. For additional psychosocial support, an emphasis on community and human connection can be helpful, as this has been shown to support a healthy immune response.


Whole Foods

Nutritional Recommendations


Encourage consumption of mushrooms such as maitake and Turkey Tail which have been shown to support a healthy immune system response. Mushrooms can positively impact the development of hematopoietic stem cells, macrophages, lymphocytes, T cells, and Natural Killer cells that support a robust immune system.


Whole food sources of probiotics can provide beneficial bacteria for the microbiome to aid in immune health and microbial diversity. A few examples of probiotic-rich foods include yogurt, kimchi, kefir, sauerkraut, miso, homemade pickles, kvass, and pickled vegetables. Probiotics have been found to both stimulate and modulate the immune system.


Recommend foods rich in Vitamins A, C, E, and selenium such as colorful fruits and vegetables like carrots, tomatoes, avocados, citrus fruits, spinach, bell peppers, Brazil nuts, and almonds. Seafood is also a rich source of Vitamin A and selenium. These antioxidants support a normal inflammatory response and support healthy white blood cell function.


Ensure intake of foods rich in zinc such as organ meat, beef, poultry, and shellfish. Zinc is an essential micronutrient for cell activities such as division and growth and has antioxidant and anti-inflammatory properties. Zinc plays a role in both innate and adaptive immune responses, making it a key nutritional building block for immune health.


Dietary Supplement Regimen:


  • Epimune Complex: Supports respiratory health and immune system activity.
    Suggested Dose: 2 capsules per day.


  • Immuplex®: Supports immune response through a blend of essential micronutrients.
    Suggested Dose: 2 capsules per day.


  • ProSynbiotic: Supports gut health and bowel regularity.
    Suggested Dose: 1 tablet 2-3 times per day.


  • Echinacea Premium: Enhances immune system function and supports upper respiratory health.
    Suggested Dose: 3 capsules per day.
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Seasonal Immune Response The innate and adaptive immune systems help regulate the body’s response to an array of potential allergens from the external environment. The immune system must distinguish between innocuous and harmful environmental antigens to avoid an exaggerated or self-destructive immune response. Potential allergens like pet dander, pollen, mold, and dust mites are constantly sampled by antigen-presenting cells (APCs) such as dendritic cells, monocytes, and macrophages. APCs process antigens and present them to T cells. T helper 2 (Th2) cells promote the release of immunoglobulins and cytokines. Antigen-dependent activation of tissue mast cells with specific IgE bound to their surface is the central event in acute allergic reactions. IgE sensitizes mast cells to release biologically active mediators like histamine and leukotrienes. Histamine is important in conditions like allergic rhinitis, urticaria, and asthma. Mast cells represent the most significant source of histamine within the immune system. Mast cells are distributed throughout nearly all vascularized tissues with relatively high numbers occurring near body surfaces including the airway epithelium. In allergic rhinitis, allergens stimulate mast cells, CD4+ T cells, B cells, macrophages, and eosinophils to infiltrate the lining of the nasal cavity and the nasal mucosa. The release of histamine and cytokines leads to uncomfortable symptoms like mucosal edema, sneezing, pruritis, rhinorrhea, and nasal congestion. Lifestyle and nutritional interventions can support a healthy seasonal immune response by stabilizing mast cells, modulating the histamine response, and reducing exposure to potential seasonal triggers. Supportive Lifestyle Practices Consider sublingual immunotherapy (SLIT) as a strategy to reorient the immune response for individuals experiencing allergy-mediated symptoms. SLIT promotes the synthesis of antibodies that block the allergen-IgE mediated complex to induce an anti-inflammatory environment. Recommend saline irrigation of the nasal passages to reduce symptoms of allergic rhinitis. This practice is thought to work by thinning nasal mucus and flushing allergens and bacteria from the nasal cavity. Encourage the use of a high-efficiency particulate air (HEPA) filter. Air purifiers that use HEPA filtration reduce airborne allergens like dust mites, animal dander, and pollen and can reduce allergic rhinitis and asthma symptoms. Whole Foods Nutritional Recommendations Encourage intake of foods rich in quercetin, which has been shown to inhibit the production and release of histamine by stabilizing the cell membrane of mast cells and preventing their activation. Onions are one of the richest food sources of quercetin. Other good sources include broccoli, bell peppers, apples, and berries. Encourage the inclusion of foods rich in omega-3 polyunsaturated fatty acids in the diet. Resolvins are lipid mediators biosynthesized from omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Resolvins can facilitate a balanced adaptive immune function and support healthy allergic airway responses by modulating the recruitment of eosinophils, lymphocytes, and macrophages. Suggest the use of raw honey in place of sugar. Honey contains phytochemicals such as gallic acid, p-coumaric acid, kaempferol, and caffeic acid that have been shown to exhibit anti-allergic effects. Emphasize the importance of consuming foods rich in vitamin D, such as the flesh and liver of fatty fish. Smaller amounts can be found in beef liver, egg yolks, and cheese. Vitamin D helps modulate adaptive immune function and supports mast cell stabilization. Dietary Supplement Regimen: Allerplex®: Supports healthy mucous membranes and respiratory function. Suggested Use: 3 capsules per meal. AllergCo: Contains Albizia and Nigella to support seasonal immune responses and respiratory function. Suggested Use: 1 tablet 4 times daily. Cod Liver Oil: Contains omega-3 fatty acids to support immune response and inflammatory processes. Suggested Use: 3 softgels per day. Antronex® : Supports the body's detoxification mechanisms. Suggested Use: 1 tablet per day.
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